Lars-Ove Brandenburg Selected Research

Formyl Peptide Receptors (Formyl Peptide Receptor)

12/2021	The N-Formyl Peptide Receptor 2 (FPR2) Agonist MR-39 Improves Ex Vivo and In Vivo Amyloid Beta (1-42)-Induced Neuroinflammation in Mouse Models of Alzheimer's Disease.
10/2020	The formyl peptide receptor agonist Ac2-26 alleviates neuroinflammation in a mouse model of pneumococcal meningitis.
4/2020	Inhibition of formyl peptide receptors improves the outcome in a mouse model of Alzheimer disease.
6/2017	Formyl Peptide Receptor 1-Mediated Glial Cell Activation in a Mouse Model of Cuprizone-Induced Demyelination.
11/2014	Lack of formyl peptide receptor 1 and 2 leads to more severe inflammation and higher mortality in mice with of pneumococcal meningitis.
1/2014	Deficiency of formyl peptide receptor 1 and 2 is associated with increased inflammation and enhanced liver injury after LPS-stimulation.
11/2012	Involvement of formyl peptide receptors in receptor for advanced glycation end products (RAGE)--and amyloid beta 1-42-induced signal transduction in glial cells.
2/2011	The formyl peptide receptor like-1 and scavenger receptor MARCO are involved in glial cell activation in bacterial meningitis.
8/2009	Involvement of Phospholipase D 1 and 2 in the subcellular localization and activity of formyl-peptide-receptors in the human colonic cell line HT29.

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Lars-Ove Brandenburg Research Topics

Disease

12	Inflammation (Inflammations) 01/2022 - 08/2009
10	Bacterial Meningitis 11/2018 - 11/2008
8	Pneumococcal Meningitis (Streptococcus pneumoniae Meningitis) 10/2020 - 02/2013
7	Alzheimer Disease (Alzheimer's Disease) 12/2021 - 06/2008
6	Neuroinflammatory Diseases 12/2021 - 07/2008
6	Muscle Cramp (Cramp) 01/2017 - 02/2011
5	Infections 10/2020 - 02/2011
5	Meningitis 10/2020 - 11/2008
5	Prostatic Neoplasms (Prostate Cancer) 10/2019 - 01/2016
4	Neoplasms (Cancer) 01/2019 - 03/2016
4	Bacterial Infections (Bacterial Infection) 02/2013 - 12/2009
3	Porcine Reproductive and Respiratory Syndrome (PRRS) 11/2019 - 06/2017
3	Demyelinating Diseases (Demyelinating Disease) 08/2018 - 04/2010
3	Neurodegenerative Diseases (Neurodegenerative Disease) 11/2012 - 05/2010
2	Gliosis 08/2018 - 01/2017
2	Meningococcal Meningitis 01/2017 - 02/2011
1	Body Weight (Weight, Body) 10/2020
1	Amyloid Plaque 04/2020
1	Leiomyosarcoma 10/2019
1	Carcinoma (Carcinomatosis) 10/2019
1	Endometrial Neoplasms (Endometrial Cancer) 10/2019
1	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 12/2017
1	Memory Disorders (Memory Loss) 01/2017
1	Liver Diseases (Liver Disease) 01/2015
1	Fibrosis (Cirrhosis) 01/2015
1	Carcinogenesis 07/2014
1	Virus Diseases (Viral Diseases) 05/2013
1	Mitochondrial Diseases (Mitochondrial Disease) 03/2012
1	Hepatitis 02/2011
1	Multiple Sclerosis 04/2010

Drug/Important Bio-Agent (IBA)

12	CytokinesIBA 01/2021 - 01/2010
11	Antimicrobial PeptidesIBA 01/2017 - 11/2008
9	Formyl Peptide Receptors (Formyl Peptide Receptor)IBA 12/2021 - 08/2009
9	CathelicidinsIBA 01/2017 - 11/2008
5	Pattern Recognition ReceptorsIBA 11/2019 - 02/2013
4	CuprizoneIBA 08/2018 - 04/2010
4	Messenger RNA (mRNA)IBA 06/2017 - 02/2013
3	MicroRNAs (MicroRNA)IBA 01/2022 - 08/2016
3	Peptides (Polypeptides)IBA 10/2020 - 01/2010
3	ChemokinesIBA 11/2018 - 08/2015
3	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 11/2012 - 05/2010
2	Amyloid (Amyloid Fibrils)IBA 12/2021 - 04/2020
2	Amyloid beta-PeptidesIBA 12/2021 - 06/2008
2	InflammasomesIBA 01/2021 - 12/2012
2	Annexin A1IBA 10/2020 - 11/2019
2	AndrogensIBA 01/2019 - 01/2016
2	S100 Calcium Binding Protein A7IBA 01/2017 - 05/2013
2	Biomarkers (Surrogate Marker)IBA 01/2017 - 10/2016
2	Interleukin-6 (Interleukin 6)IBA 01/2016 - 02/2011
2	Scavenger Receptors (Scavenger Receptor)IBA 02/2011 - 05/2010
1	Macrophage Colony-Stimulating FactorIBA 11/2019
1	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 11/2019
1	Steroid Receptors (Steroid Receptor)IBA 10/2019
1	enzalutamideIBA 10/2019
1	Heat-Shock Proteins (Heat-Shock Protein)IBA 10/2019
1	Androgen Receptor AntagonistsIBA 10/2019
1	Androgen Receptors (Androgen Receptor)IBA 10/2019
1	Estrogen ReceptorsIBA 10/2019
1	matrigelIBA 01/2019
1	Chemokine CCL3IBA 11/2018
1	Toll-Like Receptors (Toll-Like Receptor)IBA 08/2018
1	GTP-Binding Proteins (G-Protein)IBA 06/2017
1	Peptidoglycan (Murein)IBA 01/2017
1	methysticinIBA 01/2017
1	Interleukin-17 (Interleukin 17)IBA 01/2017
1	LipopolysaccharidesIBA 01/2017
1	Toll-Like Receptor 2IBA 10/2016
1	Proteins (Proteins, Gene)FDA Link 03/2016
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2016
1	HSP27 Heat-Shock ProteinsIBA 01/2016
1	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 01/2016
1	Type I Tumor Necrosis Factor ReceptorsIBA 01/2016
1	Abiraterone AcetateIBA 01/2016
1	Choline (Choline Chloride)IBA 01/2015
1	Methionine (L-Methionine)FDA Link 01/2015
1	CollagenIBA 01/2015
1	Complement C5a (Complement 5a)IBA 01/2015
1	1-dodecylpyridoxal (PLD)IBA 07/2014
1	Double-Stranded RNA (RNA, Double Stranded)IBA 05/2013
1	Poly I-CIBA 05/2013
1	CytosineIBA 02/2013
1	DNA (Deoxyribonucleic Acid)IBA 02/2013
1	Bacterial DNAIBA 02/2013
1	GuanineIBA 02/2013
1	OligodeoxyribonucleotidesIBA 02/2013
1	Mitogen-Activated Protein KinasesIBA 02/2013
1	Toll-Like Receptor 9IBA 02/2013
1	LigandsIBA 11/2012
1	Receptor for Advanced Glycation End ProductsIBA 11/2012
1	Oxidants (Oxidizing Agents)IBA 03/2012
1	Transcription Factors (Transcription Factor)IBA 02/2011
1	sulforaphaneIBA 06/2010
1	activin AIBA 01/2010
1	Prion ProteinsIBA 11/2009

Therapy/Procedure

3	Therapeutics 10/2020 - 08/2015
2	Intraventricular Infusions 08/2015 - 02/2013
1	Intraperitoneal Injections 10/2020
1	Oral Administration 01/2017
1	Ligation 01/2015
1	Aftercare (After-Treatment) 02/2013